fe227



	Material Safety Data Sheet The MSDS format adheres to U.S. standards and regulatory requirements and may not meet regulatory requirements in other countries. This information is based upon technical information believed to be reliable. It is subject to revision as additional knowledge and experience are gained. FE-227 6160FR Revised 22-SEP-2000 Printed 30-MAR-2001 CHEMICAL PRODUCT/COMPANY IDENTIFICATION Material Identification FE-227 is a registered trademark of DuPont. CAS Number : 431-89-0 Formula : CF3 CHF CF3 Molecular Weight : 170.04 CAS Name : Propane, 1,1,1,2,3,3,3-Heptafluoro- Tradenames and Synonyms HFA 227ea FC-227ea Dymel 227 ea/p 2-Hydroperfluoropropane Propane, 1,1,1,2,3,3,3-Heptafluoro- HFC-227ea 2-Hydroheptafluoropropane FM-200(tm) Great Lakes Chemical Corp. Heptafluoropropane Company Identification MANUFACTURER/DISTRIBUTOR DuPont Fluoroproducts 1007 Market Street Wilmington, DE 19898 PHONE NUMBERS Product Information : 1-800-441-7515 Transport Emergency : CHEMTREC 1-800-424-9300 Medical Emergency : 1-800-441-3637 COMPOSITION/INFORMATION ON INGREDIENTS Components Material CAS Number % 1,1,1,2,3,3,3-Heptafluoropropane 431-89-0 99+ HAZARDS IDENTIFICATION Potential Health Effects Symptoms similar to oxygen deprivation (headache, nausea, dizziness or loss of consciousness) may result from overexposure by inhalation. Gross overexposure by inhalation may cause irregular pulse, heart palpitations and potentially fatal cardiac sensitization. Cold, white or discolored skin or in severe cases blistering, can be a sign of frostbite caused by cold liquids or gases. Eyes: Direct eye contact with the liquid or cold gas can cause chilling or possibly frostbite of exposed tissues. Skin: Direct skin contact with the liquid or cold gas can cause chilling or possibly frostbite of exposed tissues. Ingestion: Not expected to be a hazard in normal industrial use. Inhalation: Inhalation of high concentrations can be harmful or fatal due to oxygen deprivation and/or heart irregularities (arrhythmias). Misuse of product by deliberately inhaling high concentrations of this gas could cause death without warning. Medical Conditions Aggravated by Exposure: Persons with pre-existing cardiac, respiratory or central nervous system disorders may be more susceptible to effects of an overexposure. Notice to Physicians: Overexposure to this material may make the heart more susceptible to arrhythmias. Catecholamines such as adrenaline and other compounds having similar effects should be reserved for emergencies and then used only with special caution. Vapors are heavier than air and pose a hazard of suffocation if trapped in enclosed or low places. Carcinogenicity Information None of the components present in this material at concentrations equal to or greater than 0.1% are listed by IARC, NTP, OSHA or ACGIH as a carcinogen. FIRST AID MEASURES First Aid INHALATION If inhaled, immediately remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Call a physician. SKIN CONTACT Treat for frostbite if necessary by gently warming affected area. EYE CONTACT In case of contact, immediately flush eyes with plenty of water for at least 15 minutes. Call a physician. INGESTION Ingestion is not considered a potential route of exposure. FIRE FIGHTING MEASURES Flammable Properties 1,1,1,2,3,3,3-Heptafluoropropane is not flammable, however in the presence of a flame or ignition source it may decompose to form toxic hydrogen fluoride or carbonyl fluoride. Non-flammable. Extinguishing Media Use media appropriate for surrounding material. Fire Fighting Instructions Self-contained breathing apparatus (SCBA) may be required if cylinders rupture or release under fire conditions. Keep cylinders cool with water spray applied from a safe distance. ACCIDENTAL RELEASE MEASURES Safeguards (Personnel) NOTE: Review FIRE FIGHTING MEASURES and HANDLING (PERSONNEL) sections before proceeding with clean-up. Use appropriate PERSONAL PROTECTIVE EQUIPMENT during clean-up. Evacuate personnel, thoroughly ventilate area, use self-contained breathing apparatus. Keep upwind of leak - evacuate until gas has dispersed. Initial Containment Use forced ventilation to disperse vapors. HANDLING AND STORAGE Handling (Personnel) Do not breathe gas. Avoid contact with eyes, skin, or clothing. Wash thoroughly after handling. Wash clothing after use. Storage Store in a well ventilated place. Store in a cool, dry place. Keep container tightly closed. EXPOSURE CONTROLS/PERSONAL PROTECTION Engineering Controls Use only with adequate ventilation. Keep container tightly closed. Personal Protective Equipment EYE/FACE PROTECTION Wear safety glasses or coverall chemical splash goggles. RESPIRATORS Wear NIOSH approved respiratory protection, as appropriate. PROTECTIVE CLOTHING Where there is potential for skin contact have available and wear as appropriate impervious gloves, apron, pants, and jacket. Exposure Guidelines Exposure Limits FE-227 AEL * (DuPont) : 1000 ppm, 8 & 12 Hr. TWA * AEL is DuPont's Acceptable Exposure Limit. Where governmentally imposed occupational exposure limits which are lower than the AEL are in effect, such limits shall take precedence. PHYSICAL AND CHEMICAL PROPERTIES Physical Data Boiling Point : -15.6 C (3.9 F) Melting Point : -133 C (-207 F) Vapor Pressure : 66.69 psia @ 25 C (77 F) (460.06 kPa) Liquid Density : 1.386 g/cm3 @ 25 C (77 F) (86.53 lb/ft3) Critical temperature : 101.6 C (214.9 F) Critical pressure : 424.7 psia (2930 kPa) Odor : Slight Ethereal Form : Liquified Gas STABILITY AND REACTIVITY Chemical Stability Stable at normal temperatures and storage conditions. Avoid sources of heat or open flame. Incompatibility with Other Materials Incompatible with strong reducing agents such as alkali metals (e.g., sodium, potassium), alkali-earth metals (e.g., magnesium, calcium), and powdered aluminum or zinc. Decomposition Decomposes by reaction with high temperature (open flames, glowing metal surfaces, etc.) forming hydrofluoric acid, carbonyl fluorides, carbon monoxide and carbon dioxide. Polymerization Polymerization will not occur. TOXICOLOGICAL INFORMATION Animal Data Groups of six rats were exposed for four hours to 25,000 or 53,000 ppm of FC-227ea. No deaths occurred. Signs of toxicity during exposure included irregular breathing, slight lacrimation and red ears. No toxic signs were seen post exposure. Animal studies have found the rat four hour LC50 to be >788,696 ppm (80%), the highest level tested. A cardiac sensitization study in dogs found the No Observable Adverse Effect Level (NOAEL) to be 9.0%. The Lowest Observable Adverse Effect Level (LOAEL) for this study was reported to be 10.5%. A 90 day inhalation study did not find any exposure related effects at 105,000 ppm (10.5% vol./vol.), the highest level tested. Tests have shown that this material does not cause genetic damage in bacterial and mammalian cell cultures. When evaluated by an in-vivo mouse micronucleus assay, no increase in micronuclei was observed. DISPOSAL CONSIDERATIONS Waste Disposal Treatment, storage, transportation, and disposal must be in accordance with applicable Federal, State/Provincial, and Local regulations. Incinerate material in accordance with Federal, State/Provincial and Local requirements. TRANSPORTATION INFORMATION Shipping Information DOT Proper Shipping Name : Heptafluoropropane Hazard Class : 2.2 I.D. No. (UN/NA) : UN 3296 DOT Label(s) : Nonflammable Gas REGULATORY INFORMATION U.S. Federal Regulations TSCA Inventory Status : Listed. TITLE III HAZARD CLASSIFICATIONS SECTIONS 311, 312 Acute : Yes Chronic : No Fire : No Reactivity : No Pressure : No OTHER INFORMATION NFPA, NPCA-HMIS NFPA Rating Health : 1 Flammability : 0 Reactivity : 1 NPCA-HMIS Rating Health : 1 Flammability : 0 Reactivity : 0 Personal Protection rating to be supplied by user depending on use conditions. Additional Information Some of the health and toxicity information was provided from a Great Lakes Chemical Corporation MSDS. ---------------------------------------------------------------------- The data in this Material Safety Data Sheet relates only to the specific material designated herein and does not relate to use in combination with any other material or in any process. Responsibility for MSDS : MSDS Coordinator > : DuPont Fluoroproducts Address : Wilmington, DE 19898 Telephone : (800) 441-7515 End of MSDS